UCLA college student Jonathan Moore (Anthony Edwards) is playing a game called "Gotcha" (popular on mid-1980s college campuses as "Assassin" or "Tag"), wherein the players are all assigned a mock "hit" on another player by use of a harmless paintball gun. Moore and his apartment roommate Manolo go on a vacation to Paris, France. After touring some of Paris, in a cafe Moore meets Sasha Banicek (Linda Fiorentino), a Czechoslovakian girl. Eventually, Jonathan has intercourse with Sasha, losing his virginity.
Jonathan decides to leave Manolo (who is heading to Spain) and go with Sasha to West Berlin to spend more time with her. Jonathan believes that he is in love with Sasha. There, Jonathan and Sasha continue to have sex and even go to an Oktoberfest beer gathering. One night, Sasha tells Jonathan that she has to go to East Berlin to pick up a package. One night after arriving in East Berlin, Sasha leaves their hotel room and walks to dark street corner. There, Sasha meets a German man who tells her the location of the pickup of her package. Meanwhile, Sasha was being monitored by a Soviet agent, who was sitting in a car at a distance. During the day, Sasha tells Jonathan that if she gives him a certain message, it means that he has to leave East Berlin immediately. At a cafe, Sasha gives Jonathan a package and says that a strudel is inside. A little later, Sasha tells Jonathan to meet her at the butcher shop near their hotel. All of a sudden, a Soviet agent begins to chase after Sasha. Sasha decides to use Jonathan (who is holding her package) to unknowingly get the package over to West Berlin. Meanwhile, Sasha is taken by the Soviet agent and East German secret police.
Jonathan goes to Checkpoint Charlie to cross the heavily fortified border into West Berlin. At the East German customs search, Jonathan is stripped of his clothes and given a cavity search. Meanwhile, Sasha is stripped and searched for possible espionage evidence. Vlad arrives at the border crossing to search for Jonathan, however Jonathan passes the border safely before he can be captured. Once in West Berlin, Jonathan feels liberated by the Westernized society. In the hotel, Jonathan receives a message from Sasha to meet him at a specified location. Jonathan finds out that his hotel room was broken into and robbed of his traveler's checks. Soviet agents eventually find Jonathan in West Berlin and chase him throughout a public park. Jonathan jumps into a water canal and manages to escape from the Soviets and stumbles upon a German rock group headed for Hamburg, who offer him a ride to the airport.
The rock group successfully get Jonathan to the airport (using full-face makeup to sneak him past a checkpoint) and Jonathan finally arrives in Los Angeles Tom Bradley International Airport and to his apartment. Soon, Vlad and a band of Soviet agents arrive too in Los Angeles. Once home, Jonathan stumbles upon a film canister, which was planted by Sasha. Jonathan visits his parents and tells them what happened in Germany but they cannot believe a word of it and think Jonathan is on drugs. Jonathan decides to call the FBI then the Central Intelligence Agency for help. Jonathan returns to find his apartment broken into and looted.
The CIA officer tells Jonathan to give them the photo film canister. At the Los Angeles headquarters of the CIA, Jonathan spots Sasha who looks like she was working there. Jonathan eventually meets up with Sasha. Sasha admits that she is Cheryl Brewster, a CIA agent, originally from Pittsburgh. Out of nowhere, Vlad and his gang begin to chase Jonathan and Cheryl on the UCLA campus. Jonathan eliminates all the Soviets with a tranquilizer gun which he gets from the campus veterinary sciences building. The Soviets are arrested, the CIA agents thank Jonathan for his (indirect) help in obtaining the film, and Sasha tells him she wants to continue their relationship.
After they part, Jonathan talks to a pretty student who rebuffs him coldly. As she walks away, he aims the tranquilizer pistol and shoots her in the rear.
竟然还不错 就是太赶了 正好在读《和我们的女儿谈话 》 有很多贯穿的地方（死亡，父母，女儿…）
梁子很正 包袱也不馊 就可惜跟预料的一样 要打到最后的呈现点子上总难免有所偏差
这干细胞的广告做的有点大啊，是为了科普吗，可是最后结局也太梦幻了
王老和萌萌就自然多了，想和这俩人做朋友。
题材非常有趣，开头也就是分分钟抓人，那种离别永恒的伤感。但是中间拖沓拉跨，还马爷干细胞乱入，这不应该去霓虹取经，到啥布拉格啊，太乱炖了。导致最后海边见面莫名其妙的画蛇添足感。感觉导演舍不得剪辑，所以一下子剪了两个结局联播。王传君不再关谷神奇后，就慢慢安藤政信化了。
纯粹是为了王传君的演技给个三星。还有，可以天马行空，但是可不可以不要乱搞实实在在的生物医学…搞生物的真的会疯。如果去掉所有乱七八糟的科研情节，明明可以是部不错的电影。
明明很烂，却用死亡、爱情，让你觉得好像是很深奥，所以看不懂的假象。
3.5，表达曾经时代“坎坷不平”的深刻立意与剧作割裂感并存的电影，说特别尴尬也不至于吧，就是要素过多会给人一种混乱不堪的感觉，不过要结合起来故事中每个人的经历来看，但这样看的话不如叫“你一生遗忘的故事”还差不多，其实每个人大大小小的事都会经历，都会有印象深刻的往事，但终究会遗忘，遗忘了，自己便不再是自己。
感觉两个小时的片子像两个导演拍的，前一个小时质感很好，剧情和智商人物逻辑都在四星的线，后一半像拍到一半没有经费了开始拉干细胞企业的经费成了大型干细胞广告，剧情和人物关系往无厘头的方向发展一直拉垮到收尾。换个名字和剪掉中间大幅讲干细胞的部分其实会是一部质感很好的作品。有点可惜。
演技都在线，但故事是个什么莫名其妙的故事？有一点点扣题吗？？？？
眼看着28岁了 ，我还单身，工作还没定 ，前路在何处，茫然失措。
1.王珞丹好像从《北辙南辕》里无缝走进了这个世界。
原以为是本杰明巴顿奇事的本土化，意外得还可以。一段横贯60年的爱情故事，叙事效率很高，野心很大，走故事情节，人物情绪比较薄，台词京味儿浓很鲜活，但前后割裂感确实强，王传君就是艾德里安 布洛迪北京分迪，摄影机观察视点，最后奔战场行使使命那段配着连绵不断的旁边确实困，最后的煽情有点楞
如果没有宏大命题+癌症+车祸+借胎生子+三角恋就好了
侧 勒 努 趯 策 掠 啄 磔——咏字八法——慨书
可惜没把时间慢行性的设定多利用一下，这个点还是挺有意思的。
你以为的不老超能力是因为小时候的化学事故，可这能力最后的来源，却让这个故事前后有了严重的割裂感，看来是不能太期待王朔写类似的故事。
女主如果是选春夏来演会更好，王珞丹演不出破碎感，市侩又不够市侩，纯又不纯…更演不出在两者间摇摆的破碎感，十分出戏…… 干细胞真厉害啊，怪不得龙人都能活那么久
割裂严重，用爱情故事包装的干细胞抗衰老广告。
干细胞有点太扯了，我以为他会老老实实成为一个好的外科医生。
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